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Gregory E D Mullen Selected Research

ProMune (CpG 7909)

1/2010Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults.
12/2009A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults.
6/2009A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals.
8/2008Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria.
7/2007Enhanced antibody production in mice to the malaria antigen AMA1 by CPG 7909 requires physical association of CpG and antigen.

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Gregory E D Mullen Research Topics

Disease

11Malaria
01/2012 - 07/2007
3Hypoxia (Hypoxemia)
07/2022 - 03/2002
3Prostatic Neoplasms (Prostate Cancer)
01/2021 - 08/2017
3Falciparum Malaria (Plasmodium falciparum Malaria)
12/2009 - 03/2006
2Neoplasms (Cancer)
07/2022 - 01/2011
2Inflammation (Inflammations)
12/2014 - 03/2013
1Adenocarcinoma
07/2022
1Carcinoma (Carcinomatosis)
07/2022
1Asthma (Bronchial Asthma)
12/2014
1Erythema
01/2010
1Infections
12/2008
1Virus Diseases (Viral Diseases)
03/2003

Drug/Important Bio-Agent (IBA)

10VaccinesIBA
01/2012 - 03/2006
7AntigensIBA
10/2017 - 07/2007
5ProMune (CpG 7909)IBA
01/2010 - 07/2007
5Aluminum Hydroxide (Algeldrate)FDA Link
01/2010 - 03/2006
3Malaria VaccinesIBA
03/2009 - 08/2008
3LigandsIBA
03/2009 - 03/2002
2Biological ProductsIBA
07/2022 - 12/2008
2Biomarkers (Surrogate Marker)IBA
07/2022 - 03/2013
2Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2012
2Recombinant ProteinsIBA
03/2010 - 06/2009
2OligodeoxyribonucleotidesIBA
03/2006 - 03/2003
2ThiosemicarbazonesIBA
03/2002 - 03/2002
1CobaltIBA
07/2022
1CuATSMIBA
07/2022
1fluoromisonidazoleIBA
07/2022
1pimonidazoleIBA
07/2022
1Oxygen (Dioxygen)IBA
07/2022
1Staphylococcal Protein A (Protein A)IBA
01/2021
1human FOLH1 proteinIBA
01/2021
1SolutionsIBA
10/2017
1Chelating AgentsIBA
10/2017
1AllergensIBA
12/2014
1Sialic Acid Binding Ig-like Lectin 1IBA
03/2013
1ferric oxide (iron oxide)IBA
01/2011
1mannide monooleateIBA
03/2010
1Merozoite Surface Protein 1 (MSA1)IBA
01/2010
1BuffersIBA
06/2009
1Phosphates (Orthophosphate)IBA
06/2009
1Hemoglobins (Hemoglobin)IBA
05/2009
1AntibodiesIBA
12/2008
1Histamine (Histamine Dihydrochloride)FDA Link
03/2003
1Histamine H2 ReceptorsIBA
03/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2003
1copper (II) diacetyl- di(N(4)- methylthiosemicarbazone)IBA
03/2002
1MetalsIBA
03/2002
1CopperIBA
03/2002

Therapy/Procedure

2Therapeutics
12/2014 - 03/2013
1Radiotherapy
07/2022
1Immunotherapy
01/2011